Brett Lyda: Guests
ABClex
November 29, 2008
It encompasses a range of health care practices evolved to maintain and restore health by the prevention and treatment of illness.
Contemporary medicine applies health science, biomedical research, and medical technology to diagnose and treat injury and disease, typically through medication, surgery, or some other form of therapy.
The word medicine is derived from the Latin ars medicina, meaning the art of healing.
Though medical technology and clinical expertise are pivotal to contemporary medicine, successful face-to-face relief of actual suffering continues to require the application of ordinary human feeling and compassion, known in English as bedside manner.
As science and technology developed, medicine became more reliant upon medications. Pharmacology developed from herbalism and many drugs are still derived from plants (atropine, ephedrine, warfarin, aspirin, digoxin, vinca alkaloids, taxol, hyoscine, etc). The first of these was arsphenamine / Salvarsan discovered by Paul Ehrlich in 1908 after he observed that bacteria took up toxic dyes that human cells did not. Vaccines were discovered by Edward Jenner and Louis Pasteur. The first major class of antibiotics was the sulfa drugs, derived by French chemists originally from azo dyes. This has become increasingly sophisticated; modern biotechnology allows drugs targeted towards specific physiological processes to be developed, sometimes designed for compatibility with the body to reduce side-effects. Genomics and knowledge of human genetics is having some influence on medicine, as the causative genes of most monogenic genetic disorders have now been identified, and the development of techniques in molecular biology and genetics are influencing medical technology, practice and decision-making.
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Sahachiro Hata discovered the anti-syphilitic activity of this compound in 1908 in the laboratory of Paul Ehrlich, during a survey of hundreds of newly synthesized organic arsenical compounds. Ehrlich had theorized that by screening many compounds a drug could be discovered with anti-microbial activity. Ehrlich's team began their search for such a "magic bullet" among chemical derivatives of the dangerously toxic drug atoxyl. This was the first organized team effort to optimize the biological activity of a lead compound through systematic chemical modifications, the basis for nearly all modern pharmaceutical research.
Arsphenamine was marketed under the trade name Salvarsan in 1910. It was also called 606, because it was the 606th compound synthesized for testing Germany it was the practice to designate compounds by their development number. Another compound known commonly in Germany by its number is Parathion, which was the 605th compound to be developed in search for insecticide. It is commonly known as E605 (E stands for Entwicklungsnummer (German for "development number")]. Salvarsan was the first organic anti-syphillitic, and a great improvement over the inorganic mercury compounds that had been used previously. A more soluble (but slightly less effective) arsenical compound, Neosalvarsan, (neoarsphenamine), became available in 1912. These arsenical compounds came with considerable risk of side effects, and they were supplanted as treatments for syphilis in the 1940s by penicillin.
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November 24, 2008
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November 24, 2008
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November 15, 2008
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November 10, 2008
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November 9, 2008
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October 23, 2008
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Trey Lyda
July 21, 2008
Que paso hermano? I love the new look & feel of the site. It contains a cornucopia of funky design. Keep up the good work. It sure is fun browsing through portals of your life. By the way, "Shit 2 Me" is a local hit here in the ATL. It never gets old (and that is a tough thing for me to say!).
We love ya!
III
Anna Malle
July 8, 2008
Your betrothed was exposed to your classlessness
Adam Polanger
June 11, 2008
rockin website dude. great pleasure workin with you.
Dave Melford
May 30, 2008
Great Music here, Let's Jam
Michael Girvigian
December 28, 2007
Jeff Nott told me you live on the same street as I do. Small World.
What up?
mika belle
September 3, 2007
keep up the great work!
Julio Crockett
November 23, 2006
That Sh!t 2 Me video is some of the funniest Sh!t I have ever seen. You are one cool cucumber, Brettsky.
wanni
November 16, 2006
I love you
Holt Lyda
November 15, 2006
Dope site, Brett. Dope. Keep the tunes flowing. Be good, brother of mine.
- Holtster
tiffany
October 7, 2006
nice site. "you're the shit" is a great song. catchy and fun, i've listened to it lots. you rock! much love, t.
LISADEE
October 4, 2006
what a beautiful site!
you are all grown up now buddy..
love love
Julius Crockpot
October 3, 2006
Dearest Brett. I am so pleased with this lovely site of yours. It is as color coordinated as your house, and that's awesome.
misha
September 30, 2006
what's the scientific term for two females having intercourse?
You can email your responses to me! Brett, I am looking forward to seeing you guys play tonight...two blocks from my home! My nipples are all a tingle! Much love, mish
tracy
September 28, 2006
cool website! who did it for you? i need to get me one of these bad boyz. may i suggest a link: www.myspace.com/tracymcmillan
just say it's your nightmare ex-girlfriend who finally has the solo project she always wanted... lol. come leave me a comment or something!!!
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September 28, 2006
Yeah bro! Lookin' great!